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The usual recommended dose is 25 to 100 mg 1 hour before sexual activity. The maximum dose is 100 mg daily. The elderly (over 65 years of age) should start at 25 mg before sexual activity. In fact, it may actually improve exercise tests. Sildenafil does not alter cardiac contractility, cardiac output or myocardial oxygen consumption based on evidence reviewed to date (Gillies et al 2024; Vlachopoulos et al 2024; Kukreja et al 2024; Webster et al 2024). Viagra comes in three dosages: 25mg, 50mg, and 100mg. Most patients start at 50mg. Sildenafil pills similarly come in 25mg, 50mg, and 100mg tablets. However, sildenafil can also come in 20mg when it is sold as the generic version of Revatio. Revatio is FDA-approved to treat a type of high blood pressure in the lungs (called pulmonary arterial sildenafil expiration date A 2.5 mg/mL sildenafil citrate oral suspension may be made with tablets and either a 1:1 mixture of methylcellulose 1% and simple syrup NF or a 1:1 mixture of Ora-Sweet and Ora-Plus. Crush thirty sildenafil 25 mg tablets (Viagra) in a mortar and reduce to a fine powder. Sildenafil should never be used in children for erectile dysfunction. In general, sildenafil should not be used for pulmonary arterial hypertension in children, especially for chronic use. Geriatric. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sildenafil in the elderly.

steady state (500 mg twice daily) with sildenafil (100 mg single dose) resulted in a 300% (4-fold) increase in sildenafil C max and a 1,000% (11-fold) increase in sildenafil plasma AUC. At 24 hours, the plasma levels of sildenafil were still approximately 200 ng/mL, compared to approximately 5 ng/mL when sildenafil was administered alone.